Overweight people with prediabetes are likely to lose more weight on a lower-carb or low-glycemic-load diet than on a higher-carb, low-fat diet, while the reverse may be true for those with normal blood sugar levels, suggests a study in the American Journal of Clinical Nutrition in 2017. Prediabetes is characterized by moderately elevated blood sugar levels, a condition that affects an estimated 86 million Americans.
Researchers analyzed data from three European clinical trials that evaluated diets with different proportions of carbs, fat, and protein. They found that while the diets performed similarly overall, when participants were grouped by their fasting blood sugar levels, those with prediabetes lost significantly more weight and kept more off when they followed a diet that was lower in carbs or high in fiber and whole grains (thus generally lower in glycemic load).
It’s well known that people respond differently to various weight-loss diets, and the researchers hypothesized that initial fasting blood sugar levels might help predict which type of diet is likely to be more successful.
Also see Medication for Prediabetes?