Long-term use of low-dose aspirin reduces the risk of colon cancer. In a study in the Annals of Internal Medicine, middle-aged women who took 100 milligrams of aspirin (a little more than a standard “baby” aspirin) every other day for at least 10 years were 20 percent less likely to develop colon cancer than those taking a placebo.
Many studies, mostly involving men, have suggested that aspirin helps prevent colon cancer. Daily aspirin use might have been even more beneficial. There was an increase in gastrointestinal bleeding and ulcers in the aspirin group, so aspirin can’t be recommended for everyone. But those at high risk for colon cancer because of family history or prior polyps should discuss aspirin therapy with their health care providers.